A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to …

Dec 10, 2025 · Monoclonal antibodies can treat autoimmune conditions, cancers and other diseases by working with your immune system.

Jun 3, 2025 · The mAb (ibritumomab) delivers a radioactive substance (Yttrium-90) directly to cancer cells. Another example is Kadcyla, an mAb that is attached to a chemotherapy drug.

Feb 15, 2026 · A monoclonal antibody (mAb) is a type of immune protein produced in a lab that binds to a specific protein on a cell called an antigen. As with naturally occurring antibodies, monoclonal …

Bevacizumab (Avastin) is an mAb that targets a protein called VEGF that affects tumor blood vessel growth. It can cause side effects such as high blood pressure, bleeding, poor wound healing, blood …

Apr 21, 2026 · Initially, monoclonal proteins were primarily used for research purposes, but their gained recognition in the late 1980s with the approval of the first mAb, muromonab-CD3, aimed at …

Jul 1, 2023 · Since lack of reactivity of T cells towards tumor cells can be attributed to CTLA-4, mAb therapy for anti-CTLA-4 effects represents a promising alternative for cancer therapy; such is the …

Mar 10, 2022 · In the late 1990s the first mAb for the treatment of cancer, Rituxin (generic name rituximab) was approved by the U.S. Food and Drug Administration (FDA). Since that time, dozens of …

Fact sheet provides information on monoclonal antibodies and the difference between vaccines and mAbs

Mar 25, 2022 · Ibritumomab tiuxetan drugs are made up of mAb drugs known as rituximab and a radioactive agent called Yttrium-90. Radiolabelled monoclonal antibody treatment is known as …