Membrane proteins are key biological players involved in myriad essential cellular processes from molecular transport, cellular communication, and signal transduction to maintaining structures within ...

Immobilized metal affinity chromatography (IMAC) is a reliable method for isolation of recombinant protein following over-expression in Escherichia coli. The polyhistidine tag (6–10 consecutive amino ...

The assignee for this patent application is Medarex, L.L.C. Reporters obtained the following quote from the background information supplied by the inventors: “The large-scale, economic purification of ...

Proteins play a key role in the life sciences - from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists at the Technical University of ...

Tedious, time-consuming, exasperating: Those are perhaps the three words that researchers use most commonly to describe protein purification. Proteins, and their little sisters the peptides, are among ...

Self-removing tags can be used for simple and effective purification of recombinant proteins and peptides. The key component of these tags is an intein, which is a protein element with the ability to ...

Self-removing affinity tags have the potential to greatly accelerate the development of new therapeutics, while providing a potentially enabling manufacturing platform for non-mAb therapeutic proteins ...

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COLD SPRING HARBOR, N.Y. (Oct. 7, 2008) – A new, user-friendly laboratory manual for protein purification and analysis has just been released by Cold Spring Harbor Laboratory Press. Designed for ...

Engineers devised a way to purify protein drugs during manufacturing. Their approach, which uses nanoparticles to rapidly crystallize proteins, could help make protein drugs more affordable and ...

There are a wide variety of protein-based drugs that are used to treat various serious conditions. Insulin is perhaps the most well-known example, which is used for life-saving treatments for diabetes ...

Proteins play a vital role in life sciences, underpinning fundamental research, biotechnology, and pharmaceutical development ...